Combined evaluation of proliferation and apoptosis to calculate IC50 of VPA-induced PANC-1 cells and assessing its effect on the Wnt signaling pathway

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Tarih
2021
Yazar
Ekici, Yeliz
Yilmaz, Abdullah
Kucuksezer, Umut Can
Gazioglu, Sema Bilgic
Yamalioglu, Zeynep Dogusan
Gurol, Ali Osman
Linn, Thomas
Tuncer, Feyza Nur
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Özet
Pancreatic ductal adenocarcinoma (PDAC) is among the most deadly cancers. Since most patients develop resistance to conventional treatments, new approaches are in urgency. Valproic acid (VPA) was shown to induce apoptosis and reduce proliferation in PANC-
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https://doi.org/10.1007/s12032-021-01560-4
http://dspace.yeniyuzyil.edu.tr:8080/xmlui/handle/20.500.12629/2115
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