Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors

dc.contributor.author	Kazan, F.
dc.contributor.author	Yagci, Z.B.
dc.contributor.author	Bai, R.
dc.contributor.author	Ozkirimli, E.
dc.contributor.author	Hamel, E.
dc.contributor.author	Ozkirimli, S.
dc.date.accessioned	2021-12-21T08:40:54Z
dc.date.available	2021-12-21T08:40:54Z
dc.date.issued	2019
dc.identifier.issn	14769271
dc.identifier.uri	https://doi.org/10.1016/j.compbiolchem.2019.05.002
dc.identifier.uri	http://dspace.yeniyuzyil.edu.tr:8080/xmlui/handle/20.500.12629/1242
dc.description.abstract	A new series of N’-(substituted phenyl)-5-chloro/iodo-3-phenyl-1H-indole-2-carbohydrazide (5, 6) and N-[2-(substituted phenyl)-4-oxo-1,3-thiazolidin-3-yl]-5-iodo/chloro-3-phenyl-1H-indole-2-carboxamide (7, 8) derivatives were synthesized and evaluated for
dc.description.sponsorship	This work was supported by the Istanbul University Scientific Research Projects Unit [project number T-721/30062005]. EO thanks Prof Amedeo Caflisch for hosting her at University of Zurich. We thank the Developmental Therapeutics Program of the National C
dc.language.iso	English
dc.publisher	Elsevier Ltd
dc.title	Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors
dc.type	Article
dc.relation.journal	Computational Biology and Chemistry
dc.identifier.startpage	512
dc.identifier.endpage	523
dc.identifier.volume	80
dc.identifier.doi	10.1016/j.compbiolchem.2019.05.002
dc.relation.volume	80