Evaluation of the effect of topical and systemic ozone application in periodontitis: an experimental study in rats

Abstract

Objective: The goal of the present study was to determine the effect of systemic and topical ozone application on alveolar bone loss (ABL) by evaluating the effect of Hypoxia-inducible factor -1 alpha (HIF-1-alpha) and receptor activator of NF-kappa B lig