SIRT6 expression and oxidative DNA damage in individuals with prediabetes and type 2 diabetes mellitus

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Date
2018
Author
Caliskan, Z.
Mutlu, T.
Guven, M.
Tuncdemir, M.
Niyazioglu, M.
Hacioglu, Y.
Dincer, Y.
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Abstract
Sirtuins (SIRTs) is a family of NAD+ dependent histone deacetylases. SIRT6 takes play in glucose homeostasis, genomic stability and DNA repair. Although increased oxidative DNA damage and decreased DNA repair activity were determined in diabetes mellitus,
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https://doi.org/10.1016/j.gene.2017.11.071
http://dspace.yeniyuzyil.edu.tr:8080/xmlui/handle/20.500.12629/2149
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