Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach

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Tarih
2020
Yazar
Mutlu, O.
Ugurel, O.M.
Sariyer, E.
Ata, O.
Inci, T.G.
Ugurel, E.
Kocer, S.
Turgut-Balik, D.
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Özet
In this study, the Nsp12–Nsp8 complex of SARS-CoV-2 was targeted with structure-based and computer-aided drug design approach because of its vital role in viral replication. Sequence analysis of RNA-dependent RNA polymerase (Nsp12) sequences from 30,366 d
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https://doi.org/10.1080/07391102.2020.1819882
http://dspace.yeniyuzyil.edu.tr:8080/xmlui/handle/20.500.12629/1207
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